Fisheries sector has been playing a significant role in global food and nutritional security. Due to the almost stagnation of capture fisheries production in recent years, the onus has shifted to the aquaculture sector to meet the rapidly increasing food demands. Aquaculture has become increasingly susceptible to disease outbreaks, primarily because of anthropogenic pressure and culture intensification to achieve higher production targets. Frequent outbreaks of devastating diseases often threaten the growth/sustainability of the aquaculture industry. Both indigenous and introduced pathogens can be present and cause diseases in aquatic organisms, resulting in production losses and raising serious concerns about consumer affordability and safety issues from foodborne infections. The concept of “One Health” also recognizes the intrinsic connections between environment, animal health and human health. In this context, Department of Aquatic Animal Health Management aims to produce qualified aquatic animal health management professionals and undertake advance research to mitigate disease-related risks and production losses in aquaculture. Department is equipped with classic microbiology, molecular biology, genomics and proteomics facilities for fish disease diagnosis, microbial diversity studies, pathogen and antimicrobial resistance risk assessment, and development of novel prophylactic/therapeutic strategies.